Practical synthesis of β-oxo benzo[d]thiazolyl sulfones: scope and limitations.
نویسندگان
چکیده
In this paper, we discuss our new synthetic approach towards functionalized benzo[d]thiazolyl (BT) sulfones, based on the reunion of alkyl BT sulfones and various electrophiles (e.g. R-CO-X, RO-CO-X, RS-CO-X, Ts-X…). All important aspects of this coupling reaction, including relevant and undesirable side reactions, are evaluated by means of calculations and competitive experiments. The scope and limitations of this method are established.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 6 شماره
صفحات -
تاریخ انتشار 2012